In 2015, she began co-starring in the web series Critical Role, on which she joins fellow voice actors in playing Dungeons & Dragons Fifth Edition. Ray produced a Batgirl fan series in 2012 called Batgirl: Spoiled, in which she played the titular character. As the election came to a close, she took up street performing on Hollywood Boulevard by tap-dancing for a short time, before eventually moving on to full-time busking by dressing up as Tinkerbell for three years. She arrived around the time of the Writers Guild strike and so, having difficulty in finding auditions, she began canvassing for the 2008 presidential election to support herself financially. Her parents supported the decision and drove her there. In 2008, at the age of 19, she moved to Los Angeles to pursue a career in entertainment. At the age of 12, she began acting at the Actors Theater of Louisville.
She hails from an extended family of Louisville farmers, having helped her grandfather with chores around his tobacco farm as she was growing up from when she was around six years old. Marisha Ray Huber was born in Mount Washington, Kentucky, the daughter of a mother who works as a dog groomer and a father who sells truck tires.